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Regulation of the Pancreatic Exocrine Differentiation Program and Morphogenesis by Onecut 1/Hnf6

BACKGROUND & AIMS: The Onecut 1 transcription factor (Oc1, a.k.a. HNF6) promotes differentiation of endocrine and duct cells of the pancreas; however, it has no known role in acinar cell differentiation. We sought to better understand the role of Oc1 in exocrine pancreas development and to ident...

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Detalles Bibliográficos
Autores principales: Kropp, Peter A., Zhu, Xiaodong, Gannon, Maureen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476890/
https://www.ncbi.nlm.nih.gov/pubmed/30831323
http://dx.doi.org/10.1016/j.jcmgh.2019.02.004