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Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification

Aortic valvular interstitial cells (VICs) isolated from patients undergoing valve replacement are commonly used as in vitro models of calcific aortic valve disease (CAVD). Standardization of VIC calcification, however, has not been implemented, which impairs comparison of results from different stud...

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Detalles Bibliográficos
Autores principales: Goto, Shinji, Rogers, Maximillian A., Blaser, Mark C., Higashi, Hideyuki, Lee, Lang H., Schlotter, Florian, Body, Simon C., Aikawa, Masanori, Singh, Sasha A., Aikawa, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476921/
https://www.ncbi.nlm.nih.gov/pubmed/31041314
http://dx.doi.org/10.3389/fcvm.2019.00049