Cargando…
Antigen Extraction and B Cell Activation Enable Identification of Rare Membrane Antigen Specific Human B Cells
Determining antigen specificity is vital for understanding B cell biology and for producing human monoclonal antibodies. We describe here a powerful method for identifying B cells that recognize membrane antigens expressed on cells. The technique depends on two characteristics of the interaction bet...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477023/ https://www.ncbi.nlm.nih.gov/pubmed/31040853 http://dx.doi.org/10.3389/fimmu.2019.00829 |