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Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer’s Disease Through Activation of BDNF-TrkB Signaling Pathway

Alzheimer’s disease (AD), a progressive neurodegenerative disease characterized by impairments of cognitive function as a result of synaptic deficits and neuronal loss, is associated with inflammation. Apelin-13, a predominant neuropeptide with inhibiting effect on inflammation, has beneficial effec...

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Detalles Bibliográficos
Autores principales: Luo, Huaiqing, Xiang, Yang, Qu, Xiangping, Liu, Huijun, Liu, Chi, Li, Guangyi, Han, Li, Qin, Xiaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477031/
https://www.ncbi.nlm.nih.gov/pubmed/31040784
http://dx.doi.org/10.3389/fphar.2019.00395