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Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer’s Disease Through Activation of BDNF-TrkB Signaling Pathway
Alzheimer’s disease (AD), a progressive neurodegenerative disease characterized by impairments of cognitive function as a result of synaptic deficits and neuronal loss, is associated with inflammation. Apelin-13, a predominant neuropeptide with inhibiting effect on inflammation, has beneficial effec...
Autores principales: | Luo, Huaiqing, Xiang, Yang, Qu, Xiangping, Liu, Huijun, Liu, Chi, Li, Guangyi, Han, Li, Qin, Xiaoqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477031/ https://www.ncbi.nlm.nih.gov/pubmed/31040784 http://dx.doi.org/10.3389/fphar.2019.00395 |
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