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Family-Based Haplotype Estimation and Allele Dosage Correction for Polyploids Using Short Sequence Reads

DNA sequence reads contain information about the genomic variants located on a single chromosome. By extracting and extending this information using the overlaps between the reads, the haplotypes of an individual can be obtained. Using parent-offspring relationships in a population can considerably...

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Detalles Bibliográficos
Autores principales: Motazedi, Ehsan, Maliepaard, Chris, Finkers, Richard, Visser, Richard, de Ridder, Dick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477055/
https://www.ncbi.nlm.nih.gov/pubmed/31040862
http://dx.doi.org/10.3389/fgene.2019.00335