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Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space

Immunodominant T cell epitopes preferentially targeted in multiple individuals are the critical element of successful vaccines and targeted immunotherapies. However, the underlying principles of this “convergence” of adaptive immunity among different individuals remain poorly understood. To quantita...

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Detalles Bibliográficos
Autores principales: Ogishi, Masato, Yotsuyanagi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477061/
https://www.ncbi.nlm.nih.gov/pubmed/31057550
http://dx.doi.org/10.3389/fimmu.2019.00827