Cargando…

Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space

Immunodominant T cell epitopes preferentially targeted in multiple individuals are the critical element of successful vaccines and targeted immunotherapies. However, the underlying principles of this “convergence” of adaptive immunity among different individuals remain poorly understood. To quantita...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ogishi, Masato, Yotsuyanagi, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477061/ https://www.ncbi.nlm.nih.gov/pubmed/31057550 http://dx.doi.org/10.3389/fimmu.2019.00827

Ejemplares similares

Prediction of HIV-associated neurocognitive disorder (HAND) from three genetic features of envelope gp120 glycoprotein
por: Ogishi, Masato, et al.
Publicado: (2018)

Delineation of autoantibody repertoire through differential proteogenomics in hepatitis C virus-induced cryoglobulinemia
por: Ogishi, Masato, et al.
Publicado: (2016)

Humoral Alloimmunity in Transplantation: Relevance of HLA Epitope Antigenicity and Immunogenicity
por: Duquesnoy, René J.
Publicado: (2011)

Comprehensive Evaluation of the Expressed CD8+ T Cell Epitope Space Using High-Throughput Epitope Mapping
por: Lehmann, Paul V., et al.
Publicado: (2019)

Development and validation of immunogenic cell death-related signature for predicting the prognosis and immune landscape of uveal melanoma
por: Hu, Yuanyuan, et al.
Publicado: (2022)

Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence
por: Federico, Lorenzo, et al.
Publicado: (2023)

Immunogenicity of Potential CD4(+) and CD8(+) T Cell Epitopes Derived From the Proteome of Leishmania braziliensis
por: e Silva, Rafael de Freitas, et al.
Publicado: (2020)

Sensitization of Tumors for Attack by Virus-Specific CD8+ T-Cells Through Antibody-Mediated Delivery of Immunogenic T-Cell Epitopes
por: Sefrin, Julian P., et al.
Publicado: (2019)

Immunogenic self-peptides - the great unknowns in autoimmunity: Identifying T-cell epitopes driving the autoimmune response in autoimmune diseases
por: Prinz, Jörg Christoph
Publicado: (2023)

Accurate Prediction of Immunogenic T-Cell Epitopes from Epitope Sequences Using the Genetic Algorithm-Based Ensemble Learning
por: Zhang, Wen, et al.
Publicado: (2015)

Immunogenicity of a Multi-Epitope DNA Vaccine Encoding Epitopes from Cu–Zn Superoxide Dismutase and Open Reading Frames of Brucella abortus in Mice
por: Escalona, Emilia, et al.
Publicado: (2017)

Immunogenicity and Protective Efficacy of T-Cell Epitopes Derived From Potential Th1 Stimulatory Proteins of Leishmania (Leishmania) donovani
por: Joshi, Sumit, et al.
Publicado: (2019)

T Cell Epitope Prediction and Its Application to Immunotherapy
por: Schaap-Johansen, Anna-Lisa, et al.
Publicado: (2021)

Combining deep mutational scanning to heatmap of HLA class II binding of immunogenic sequences to preserve functionality and mitigate predicted immunogenicity
por: Sivelle, Coline, et al.
Publicado: (2023)

Immunogenic landscape and risk score prediction based on unfolded protein response (UPR)-related molecular subtypes in hepatocellular carcinoma
por: Guo, Hanyao, et al.
Publicado: (2023)

Immunogenic epitope scanning in bacteriolytic enzymes Pal and Cpl-1 and engineering Pal to escape antibody responses
por: Harhala, Marek Adam, et al.
Publicado: (2023)

Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden
por: Georgoulias, George, et al.
Publicado: (2022)

ProTECT—Prediction of T-Cell Epitopes for Cancer Therapy
por: Rao, Arjun A., et al.
Publicado: (2020)

Usefulness of the Nonself-Self Algorithm of HLA Epitope Immunogenicity in the Specificity Analysis of Monospecific Antibodies Induced during Pregnancy
por: Duquesnoy, Rene J., et al.
Publicado: (2015)

Surveillance of SARS-CoV-2 immunogenicity: loss of immunodominant HLA-A*02-restricted epitopes that activate CD8(+) T cells
por: Lopes-Ribeiro, Ágata, et al.
Publicado: (2023)

High-Throughput B Cell Epitope Determination by Next-Generation Sequencing
por: Walker, Lauren M., et al.
Publicado: (2022)

Detection of Enriched T Cell Epitope Specificity in Full T Cell Receptor Sequence Repertoires
por: Gielis, Sofie, et al.
Publicado: (2019)

Comprehending B-Cell Epitope Prediction to Develop Vaccines and Immunodiagnostics
por: Caoili, Salvador Eugenio C.
Publicado: (2022)

Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma
por: Murata, Kenji, et al.
Publicado: (2020)

Structure Based Prediction of Neoantigen Immunogenicity
por: Riley, Timothy P., et al.
Publicado: (2019)

Epitope Specific Antibodies and T Cell Receptors in the Immune Epitope Database
por: Mahajan, Swapnil, et al.
Publicado: (2018)

Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope
por: MacLachlan, Bruce J., et al.
Publicado: (2019)

Discordance Between the Predicted Versus the Actually Recognized CD8+ T Cell Epitopes of HCMV pp65 Antigen and Aleatory Epitope Dominance
por: Lehmann, Alexander A., et al.
Publicado: (2021)

Immunogenicity of a Virus-Like-Particle Vaccine Containing Multiple Antigenic Epitopes of Toxoplasma gondii Against Acute and Chronic Toxoplasmosis in Mice
por: Guo, Jingjing, et al.
Publicado: (2019)

Deconvoluting the Composition of Low-Frequency Hepatitis C Viral Quasispecies: Comparison of Genotypes and NS3 Resistance-Associated Variants between HCV/HIV Coinfected Hemophiliacs and HCV Monoinfected Patients in Japan
por: Ogishi, Masato, et al.
Publicado: (2015)

Immunosuppressive landscape in hepatocellular carcinoma revealed by single-cell sequencing
por: Bai, Yi, et al.
Publicado: (2022)

Advances in T-Cell Epitope Engineering
por: Pentier, Johanne M., et al.
Publicado: (2013)

Immunogenicity and Protective Potential of Mucosal Vaccine Formulations Based on Conserved Epitopes of Influenza A Viruses Fused to an Innovative Ring Nanoplatform in Mice and Chickens
por: Calzas, Cynthia, et al.
Publicado: (2021)

Structural basis for T cell recognition of cancer neoantigens and implications for predicting neoepitope immunogenicity
por: Mariuzza, Roy A., et al.
Publicado: (2023)

Analysis of immunogenic cell death in ascending thoracic aortic aneurysms based on single-cell sequencing data
por: Tian, Zemin, et al.
Publicado: (2023)

Predicting HLA CD4 Immunogenicity in Human Populations
por: Dhanda, Sandeep Kumar, et al.
Publicado: (2018)

SEMA: Antigen B-cell conformational epitope prediction using deep transfer learning
por: Shashkova, Tatiana I., et al.
Publicado: (2022)

Quantification of HLA-DM-Dependent Major Histocompatibility Complex of Class II Immunopeptidomes by the Peptide Landscape Antigenic Epitope Alignment Utility
por: Álvaro-Benito, Miguel, et al.
Publicado: (2018)

Prediction of celiac disease associated epitopes and motifs in a protein
por: Tomer, Ritu, et al.
Publicado: (2023)

Predicting the Effectiveness of Hepatitis C Virus Neutralizing Antibodies by Bioinformatic Analysis of Conserved Epitope Residues Using Public Sequence Data
por: Cowton, Vanessa M., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cntal7kd7snvp071ge220m59kd