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Non-coding and Coding Transcriptional Profiles Are Significantly Altered in Pediatric Retinoblastoma Tumors

Retinoblastoma is a rare pediatric tumor of the retina, caused by the homozygous loss of the Retinoblastoma 1 (RB1) tumor suppressor gene. Previous microarray studies have identified changes in the expression profiles of coding genes; however, our understanding of how non-coding genes change in this...

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Detalles Bibliográficos
Autores principales: Rajasekaran, Swetha, Nagarajha Selvan, Lakshmi Dhevi, Dotts, Kathleen, Kumar, Ranjith, Rishi, Pukhraj, Khetan, Vikas, Bisht, Madhoolika, Sivaraman, Karthikeyan, Krishnakumar, Subrmanian, Sahoo, Debashis, Campbell, Moray J., Elchuri, Sailaja V., Miles, Wayne O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477087/
https://www.ncbi.nlm.nih.gov/pubmed/31058073
http://dx.doi.org/10.3389/fonc.2019.00221