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The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria

Xenophagy, a selective autophagy pathway that protects the cytosol against bacterial invasion, relies on cargo receptors that juxtapose bacteria and phagophore membranes. Whether phagophores are recruited from a constitutive pool or are generated de novo at prospective cargo remains unknown. Phagoph...

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Detalles Bibliográficos
Autores principales: Ravenhill, Benjamin J., Boyle, Keith B., von Muhlinen, Natalia, Ellison, Cara J., Masson, Glenn R., Otten, Elsje G., Foeglein, Agnes, Williams, Roger, Randow, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477152/
https://www.ncbi.nlm.nih.gov/pubmed/30853402
http://dx.doi.org/10.1016/j.molcel.2019.01.041