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Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes

The convergence of two DNA replication forks creates unique problems during DNA replication termination. In E. coli and SV40, the release of torsional strain by type II topoisomerases is critical for converging replisomes to complete DNA synthesis, but the pathways that mediate fork convergence in e...

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Detalles Bibliográficos
Autores principales: Deegan, Tom D., Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T.P., Labib, Karim P.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477153/
https://www.ncbi.nlm.nih.gov/pubmed/30850330
http://dx.doi.org/10.1016/j.molcel.2019.01.040