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Computer-aided identification of protein targets of four polyphenols in Alzheimer’s disease (AD) and validation in a mouse AD model

Natural polyphenols are a large class of phytochemicals with neuroprotective effects. Four polyphenolic compounds: hesperidin, icariin, dihydromyricetin and baicalin were selected to evaluate their effects on Alzheimer’s disease (AD). We analyzed by an inverse docking procedure (INVDOCK) the potenti...

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Detalles Bibliográficos
Autores principales: Li, Chaoyun, Meng, Ping, Zhang, Benzheng, Kang, Hong, Wen, Hanli, Schluesener, Hermann, Cao, Zhiwei, Zhang, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477175/
https://www.ncbi.nlm.nih.gov/pubmed/30249814
http://dx.doi.org/10.7555/JBR.32.20180021