Cargando…

Computer-aided identification of protein targets of four polyphenols in Alzheimer’s disease (AD) and validation in a mouse AD model

Natural polyphenols are a large class of phytochemicals with neuroprotective effects. Four polyphenolic compounds: hesperidin, icariin, dihydromyricetin and baicalin were selected to evaluate their effects on Alzheimer’s disease (AD). We analyzed by an inverse docking procedure (INVDOCK) the potenti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Chaoyun, Meng, Ping, Zhang, Benzheng, Kang, Hong, Wen, Hanli, Schluesener, Hermann, Cao, Zhiwei, Zhang, Zhiyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477175/ https://www.ncbi.nlm.nih.gov/pubmed/30249814 http://dx.doi.org/10.7555/JBR.32.20180021

Ejemplares similares

Icariin Ameliorates Neuropathological Changes, TGF-β1 Accumulation and Behavioral Deficits in a Mouse Model of Cerebral Amyloidosis
por: Zhang, Zhi-Yuan, et al.
Publicado: (2014)

Characterization of the chromatin accessibility in an Alzheimer’s disease (AD) mouse model
por: Wang, Yaqi, et al.
Publicado: (2020)

Detection of severity in Alzheimer's disease (AD) using computational modeling
por: Kim, Hyunjo
Publicado: (2018)

Triptolide treatment reduces Alzheimer’s disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD
por: Wang, Qi, et al.
Publicado: (2014)

Disease progression modelling from preclinical Alzheimer’s disease (AD) to AD dementia
por: Cho, Soo Hyun, et al.
Publicado: (2021)

Predicting AD Conversion: Comparison between Prodromal AD Guidelines and Computer Assisted PredictAD Tool
por: Liu, Yawu, et al.
Publicado: (2013)

Genetics of Aggression in Alzheimer’s Disease (AD)
por: Lukiw, Walter J., et al.
Publicado: (2017)

AdS/CFT and BPS Strings in Four Dimensions
por: Alishahiha, M, et al.
Publicado: (1999)

Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD
por: Colton, Carol A, et al.
Publicado: (2006)

Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD
por: Lee, Hyun-ju, et al.
Publicado: (2023)

Chronic Anatabine Treatment Reduces Alzheimer’s Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD
por: Verma, Megha, et al.
Publicado: (2015)

Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer’s disease (AD) mouse model and is increased at early stage in sporadic AD brain
por: Valverde, Audrey, et al.
Publicado: (2021)

Pathogenic microbes, the microbiome, and Alzheimer’s disease (AD)
por: Hill, James M., et al.
Publicado: (2014)

Microbial-generated amyloids and Alzheimer's disease (AD)
por: Hill, James M., et al.
Publicado: (2015)

Treating Alzheimer’s Disease (AD) with Light and Sound
por: Lukiw, Walter J
Publicado: (2020)

Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Stimmell, Alina C., et al.
Publicado: (2019)

Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Javonillo, Dominic I., et al.
Publicado: (2022)

Abnormal whisker movements in the 3xTg‐AD mouse model of Alzheimer's disease
por: Simanaviciute, Ugne, et al.
Publicado: (2022)

Longitudinal Analysis of the Microbiome and Metabolome in the 5xfAD Mouse Model of Alzheimer’s Disease
por: Dunham, Sage J. B., et al.
Publicado: (2022)

Adding Pseudo-Observables to the Four-Lepton Experimentalist's Toolbox
por: Gainer, James S., et al.
Publicado: (2018)

Four-point correlation functions in the AdS/CFT correspondence
por: Chalmers, G, et al.
Publicado: (1998)

Correction: Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD
por: Verma, Megha, et al.
Publicado: (2015)

Clinical and Biomarker Characteristics According to Clinical Spectrum of Alzheimer’s Disease (AD) in the Validation Cohort of Korean Brain Aging Study for the Early Diagnosis and Prediction of AD
por: Hwang, Jihye, et al.
Publicado: (2019)

Non-alcoholic fatty liver disease induces signs of Alzheimer’s disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD model
por: Kim, Do-Geun, et al.
Publicado: (2016)

Decrease in naturally occurring antibodies against epitopes of Alzheimer’s disease (AD) risk gene products is associated with cognitive decline in AD
por: Gu, Dongmei, et al.
Publicado: (2023)

Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD
por: Han, Kyung-Min, et al.
Publicado: (2020)

AD OK for 2K AD
Publicado: (1999)

Computer-Aided Screening and Revealing Action Mechanism of Green Tea Polyphenols Intervention in Alzheimer’s Disease
por: Wang, Min, et al.
Publicado: (2023)

Brain Region-Dependent Alternative Splicing of Alzheimer Disease (AD)-Risk Genes Is Associated With Neuropathological Features in AD
por: Kim, Sara, et al.
Publicado: (2022)

Increased Hippocampal Excitability in the 3xTgAD Mouse Model for Alzheimer's Disease In Vivo
por: Davis, Katherine E., et al.
Publicado: (2014)

Progressive Vascular Abnormalities in the Aging 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Jullienne, Amandine, et al.
Publicado: (2022)

Alzheimer's disease (AD) as a disorder of the plasma membrane
por: Lukiw, Walter J.
Publicado: (2013)

Aluminum and its potential contribution to Alzheimer's disease (AD)
por: Bhattacharjee, Surjyadipta, et al.
Publicado: (2014)

Circular RNA (circRNA) in Alzheimer's disease (AD)
por: Lukiw, Walter J.
Publicado: (2013)

Biomarkers for Alzheimer’s Disease (AD) and the Application of Precision Medicine
por: Lukiw, Walter J., et al.
Publicado: (2020)

microRNA-Based Biomarkers in Alzheimer’s Disease (AD)
por: Zhao, Yuhai, et al.
Publicado: (2020)

AD Course Map charts Alzheimer’s disease progression
por: Koval, Igor, et al.
Publicado: (2021)

Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology
por: Potjewyd, Frances M., et al.
Publicado: (2022)

Oridonin ameliorates neuropathological changes and behavioural deficits in a mouse model of cerebral amyloidosis
por: Zhang, Zhi-Yuan, et al.
Publicado: (2013)

Air Pollution and Atopic Dermatitis (AD): The Impact of Particulate Matter (PM(10)) on an AD Mouse-Model
por: Woo, Yu Ri, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3gk6hte9v15ci72s36eibetsvl