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Genetic identification of brain cell types underlying schizophrenia

With few exceptions, the marked advances in knowledge about the genetic basis of schizophrenia have not converged on findings that can be confidently used for precise experimental modeling. Applying knowledge of the cellular taxonomy of the brain from single-cell RNA-sequencing, we evaluated whether...

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Detalles Bibliográficos
Autores principales: Skene, Nathan G, Bryois, Julien, Bakken, Trygve E, Breen, Gerome, Crowley, James J, Gaspar, Héléna A, Giusti-Rodriguez, Paola, Hodge, Rebecca D, Miller, Jeremy A, Muñoz-Manchado, Ana B, O’Donovan, Michael C, Owen, Michael J, Pardiñas, Antonio F, Ryge, Jesper, Walters, James T R, Linnarsson, Sten, Lein, Ed S, Sullivan, Patrick F, Hjerling-Leffler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477180/
https://www.ncbi.nlm.nih.gov/pubmed/29785013
http://dx.doi.org/10.1038/s41588-018-0129-5