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Safety and tolerability of subcutaneous sarilumab and intravenous tocilizumab in patients with rheumatoid arthritis

OBJECTIVE: Safety and efficacy of mAbs blocking the IL-6 receptor have been established in RA. This is the first analysis examining safety and tolerability of sarilumab and tocilizumab administered as single or multiple doses in patients with RA within the same study. METHODS: In ASCERTAIN, patients...

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Detalles Bibliográficos
Autores principales: Emery, Paul, Rondon, Juan, Parrino, Janie, Lin, Yong, Pena-Rossi, Claudia, van Hoogstraten, Hubert, Graham, Neil M H, Liu, Nancy, Paccaly, Anne, Wu, Richard, Spindler, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477522/
https://www.ncbi.nlm.nih.gov/pubmed/30590833
http://dx.doi.org/10.1093/rheumatology/key361