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Pharmacokinetic Profile of Inhaled Submicron Particle Paclitaxel (NanoPac(®)) in a Rodent Model

Background: Inhaled chemotherapeutics may enhance pulmonary drug exposure to malignant lesions in the lung without substantially contributing to systemic toxicities. The pharmacokinetic profile of inhaled submicron particle paclitaxel (NanoPac(®)) in healthy rodent plasma and lung tissue is evaluate...

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Detalles Bibliográficos
Autores principales: Verco, James, Johnston, William, Baltezor, Michael, Kuehl, Philip J., Gigliotti, Andrew, Belinsky, Steven A., Lopez, Anita, Wolff, Ronald, Hylle, Lauren, diZerega, Gere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477588/
https://www.ncbi.nlm.nih.gov/pubmed/30359162
http://dx.doi.org/10.1089/jamp.2018.1467