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Protection of Kidney Function with Human Antioxidation Protein α(1)-Microglobulin in a Mouse (177)Lu-DOTATATE Radiation Therapy Model

Aims: Peptide receptor radionuclide therapy (PRRT) is in clinical use today to treat metastatic neuroendocrine tumors. Infused, radiolabeled, somatostatin analog peptides target tumors that are killed by irradiation damage. The peptides, however, are also retained in kidneys due to glomerular filtra...

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Detalles Bibliográficos
Autores principales: Kristiansson, Amanda, Ahlstedt, Jonas, Holmqvist, Bo, Brinte, Anders, Tran, Thuy A., Forssell-Aronsson, Eva, Strand, Sven-Erik, Gram, Magnus, Åkerström, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477591/
https://www.ncbi.nlm.nih.gov/pubmed/29943622
http://dx.doi.org/10.1089/ars.2018.7517