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Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner

BACKGROUND: Oxidative stress and neuroinflammation are considered the major central events in the process of Parkinson’s disease (PD). Nrf2 is a key regulator of endogenous defense systems. New finds have contacted activation of Nrf2 signaling with anti-inflammatory activities. Therefore, the outsta...

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Detalles Bibliográficos
Autores principales: Zhang, Bei, Wang, Guoqing, He, Jingyi, Yang, Qiuyu, Li, Daidi, Li, Jingjie, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477740/
https://www.ncbi.nlm.nih.gov/pubmed/31010422
http://dx.doi.org/10.1186/s12974-019-1472-x