LKB1 and YAP phosphorylation play important roles in Celastrol-induced β-catenin degradation in colorectal cancer

Wnt/β-catenin and Hippo pathways play essential roles in the tumorigenesis and development of colorectal cancer. We found that Celastrol, isolated from Tripterygium wilfordii plant, exerted a significant inhibitory effect on colorectal cancer cell growth in vitro and in vivo, and further unraveled t...

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Detalles Bibliográficos
Autores principales: Wang, Shuren, Ma, Kai, Zhou, Cuiqi, Wang, Yu, Hu, Guanghui, Chen, Lechuang, Li, Zhuo, Hu, Chenfei, Xu, Qing, Zhu, Hongxia, Liu, Mei, Xu, Ningzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477772/
https://www.ncbi.nlm.nih.gov/pubmed/31040884
http://dx.doi.org/10.1177/1758835919843736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477772/
https://www.ncbi.nlm.nih.gov/pubmed/31040884
http://dx.doi.org/10.1177/1758835919843736

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