Cargando…
Exome sequencing of the TCL1 mouse model for CLL reveals genetic heterogeneity and dynamics during disease development
The TCL1 mouse model is widely used to study pathophysiology, clonal evolution, and drug sensitivity or resistance of chronic lymphocytic leukemia (CLL). By performing whole exome sequencing, we present the genetic landscape of primary tumors from TCL1 mice and of TCL1 tumors serially transplanted i...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477797/ https://www.ncbi.nlm.nih.gov/pubmed/30262843 http://dx.doi.org/10.1038/s41375-018-0260-4 |