smCounter2: an accurate low-frequency variant caller for targeted sequencing data with unique molecular identifiers

MOTIVATION: Low-frequency DNA mutations are often confounded with technical artifacts from sample preparation and sequencing. With unique molecular identifiers (UMIs), most of the sequencing errors can be corrected. However, errors before UMI tagging, such as DNA polymerase errors during end repair...

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Detalles Bibliográficos
Autores principales: Xu, Chang, Gu, Xiujing, Padmanabhan, Raghavendra, Wu, Zhong, Peng, Quan, DiCarlo, John, Wang, Yexun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477992/
https://www.ncbi.nlm.nih.gov/pubmed/30192920
http://dx.doi.org/10.1093/bioinformatics/bty790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477992/
https://www.ncbi.nlm.nih.gov/pubmed/30192920
http://dx.doi.org/10.1093/bioinformatics/bty790

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