Cargando…

Synthesis and Anticancer Activity Evaluation of Novel Phenanthridine Derivatives

Based on the structure of sanguinarine, fourteen phenanthridine derivatives were designed and synthesized in the current study. The cytotoxic activities of synthesized compounds were evaluated against five human cancer cell lines (MCF-7, PC3, Hela, A549, and HepG2 cell lines) via MTT assay. Among al...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, Minghui, Zhang, Lei, Chen, Yiming, Li, Qiang, Fan, Wenli, Xue, Qingxia, Yan, Fang, Song, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478010/
https://www.ncbi.nlm.nih.gov/pubmed/31058081
http://dx.doi.org/10.3389/fonc.2019.00274