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Synthesis and Anticancer Activity Evaluation of Novel Phenanthridine Derivatives
Based on the structure of sanguinarine, fourteen phenanthridine derivatives were designed and synthesized in the current study. The cytotoxic activities of synthesized compounds were evaluated against five human cancer cell lines (MCF-7, PC3, Hela, A549, and HepG2 cell lines) via MTT assay. Among al...
Autores principales: | Wan, Minghui, Zhang, Lei, Chen, Yiming, Li, Qiang, Fan, Wenli, Xue, Qingxia, Yan, Fang, Song, Weiguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478010/ https://www.ncbi.nlm.nih.gov/pubmed/31058081 http://dx.doi.org/10.3389/fonc.2019.00274 |
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