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Characterization of BTBD1 and BTBD2, two similar BTB-domain-containing Kelch-like proteins that interact with Topoisomerase I

BACKGROUND: Two-hybrid screening for proteins that interact with the core domain of human topoisomerase I identified two novel proteins, BTBD1 and BTBD2, which share 80% amino acid identities. RESULTS: The interactions were confirmed by co-precipitation assays demonstrating the physical interaction...

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Detalles Bibliográficos
Autores principales: Xu, Lixin, Yang, Lihong, Hashimoto, Keiko, Anderson, Melvin, Kohlhagen, Glenda, Pommier, Yves, D'Arpa, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64781/
https://www.ncbi.nlm.nih.gov/pubmed/11818025
http://dx.doi.org/10.1186/1471-2164-3-1