Cargando…

The long and the short of it: the MDM4 tail so far

The mouse double minute 4 (MDM4) is emerging from the shadow of its more famous relative MDM2 and is starting to steal the limelight, largely due to its therapeutic possibilities. MDM4 is a vital regulator of the tumor suppressor p53. It restricts p53 transcriptional activity and also, at least in d...

Descripción completa

Detalles Bibliográficos
Autores principales: Haupt, Sue, Mejía-Hernández, Javier Octavio, Vijayakumaran, Reshma, Keam, Simon P, Haupt, Ygal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478121/
https://www.ncbi.nlm.nih.gov/pubmed/30689920
http://dx.doi.org/10.1093/jmcb/mjz007