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Drugging in the absence of p53

Inactivation of the p53 gene is a key driver of tumorigenesis in various cancer cohorts and types. The quest for a successful p53-based therapy that holds the promise of treating more than half of the cancer population has culminated in extensive knowledge about the role and function of p53 and led...

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Detalles Bibliográficos
Autores principales: Aning, Obed Akwasi, Cheok, Chit Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478123/
https://www.ncbi.nlm.nih.gov/pubmed/30865230
http://dx.doi.org/10.1093/jmcb/mjz012