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Lassa Virus Targeting of Anterior Uvea and Endothelium of Cornea and Conjunctiva in Eye of Guinea Pig Model

Lassa virus (LASV), a hemorrhagic fever virus endemic to West Africa, causes conjunctivitis in patients with acute disease. To examine ocular manifestations of LASV, we histologically examined eyes from infected guinea pigs. In fatal disease, LASV immunostaining was most prominent in the anterior uv...

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Detalles Bibliográficos
Autores principales: Gary, Joy M., Welch, Stephen R., Ritter, Jana M., Coleman-McCray, JoAnn, Huynh, Thanhthao, Kainulainen, Markus H., Bollweg, Brigid C., Parihar, Vaunita, Nichol, Stuart T., Zaki, Sherif R., Spiropoulou, Christina F., Spengler, Jessica R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478213/
https://www.ncbi.nlm.nih.gov/pubmed/31002065
http://dx.doi.org/10.3201/eid2505.181254