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Structural and diffusion weighted MRI demonstrates responses to ibrutinib in a mouse model of follicular helper (Tfh) T-cell lymphoma

Recent analyses of the genetics of peripheral T-cell lymphoma (PTCL) have shown that a large proportion of cases are derived from normal follicular helper (Tfh) T-cells. The sanroque mouse strain bears a mutation that increases Tfh cell number and heterozygous animals (Roquin(san/+)) develop lymphom...

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Detalles Bibliográficos
Autores principales: Allchin, Rebecca L., Kelly, Michael E., Mamand, Sami, Doran, Anthony G., Keane, Thomas, Ahearne, Matthew J., Wagner, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478326/
https://www.ncbi.nlm.nih.gov/pubmed/31013298
http://dx.doi.org/10.1371/journal.pone.0215765