FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells

Maintenance of a healthy proteome is essential for cellular homeostasis and loss of proteostasis is associated with tissue dysfunction and neurodegenerative disease. The mechanisms that support proteostasis in healthy cells and how they become defective during aging or in disease states are not full...

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Detalles Bibliográficos
Autores principales: Audesse, Amanda J., Dhakal, Shleshma, Hassell, Lexi-Amber, Gardell, Zachary, Nemtsova, Yuliya, Webb, Ashley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478346/
https://www.ncbi.nlm.nih.gov/pubmed/30973875
http://dx.doi.org/10.1371/journal.pgen.1008097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478346/
https://www.ncbi.nlm.nih.gov/pubmed/30973875
http://dx.doi.org/10.1371/journal.pgen.1008097

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