Superior lentiviral vectors designed for BSL-0 environment abolish vector mobilization.

Lentiviral vector mobilization following HIV-1 infection of vector-transduced cells poses biosafety risks to vector-treated patients and their communities. The self-inactivating (SIN) vector design has reduced, however, not abolished mobilization of integrated vector genomes. Furthermore, an earlier...

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Detalles Bibliográficos
Autores principales: Hu, Peirong, Bi, Yanmin, Ma, Hong, Suwanmanee, Thipparat, Zeithaml, Brian, Fry, Nate J., Kohn, Donald B., Kafri, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478381/
https://www.ncbi.nlm.nih.gov/pubmed/30190607
http://dx.doi.org/10.1038/s41434-018-0039-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478381/
https://www.ncbi.nlm.nih.gov/pubmed/30190607
http://dx.doi.org/10.1038/s41434-018-0039-2

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