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Superior lentiviral vectors designed for BSL-0 environment abolish vector mobilization.
Lentiviral vector mobilization following HIV-1 infection of vector-transduced cells poses biosafety risks to vector-treated patients and their communities. The self-inactivating (SIN) vector design has reduced, however, not abolished mobilization of integrated vector genomes. Furthermore, an earlier...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478381/ https://www.ncbi.nlm.nih.gov/pubmed/30190607 http://dx.doi.org/10.1038/s41434-018-0039-2 |