Glucocorticoid‐Induced Autophagy Protects Osteocytes Against Oxidative Stress Through Activation of MAPK/ERK Signaling

Autophagy confers protective or detrimental effects on cells depending on the cellular context. We showed here that oxidative stress‐induced cell death in osteocytic MLO‐Y4 cells coincided with decreased autophagy. Decreased autophagy was also observed in osteocytes of superoxide dismutase 1‐ (SOD1‐...

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Detalles Bibliográficos
Autores principales: Kar, Rekha, Riquelme, Manuel A., Hua, Rui, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478584/
https://www.ncbi.nlm.nih.gov/pubmed/31044179
http://dx.doi.org/10.1002/jbm4.10077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478584/
https://www.ncbi.nlm.nih.gov/pubmed/31044179
http://dx.doi.org/10.1002/jbm4.10077

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