ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation

Pemphigus is an autoimmune blistering disease targeting the desmosomal proteins desmoglein (Dsg) 1 and Dsg3. Recently, a genetic variant of the Suppression of tumorigenicity 18 (ST18) promoter was reported to cause ST18 up-regulation, associated with pemphigus vulgaris (PV)-IgG-mediated increase in...

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Detalles Bibliográficos
Autores principales: Radeva, Mariya Y., Walter, Elias, Stach, Ramona Alexandra, Yazdi, Amir S., Schlegel, Nicolas, Sarig, Ofer, Sprecher, Eli, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478701/
https://www.ncbi.nlm.nih.gov/pubmed/31057535
http://dx.doi.org/10.3389/fimmu.2019.00770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478701/
https://www.ncbi.nlm.nih.gov/pubmed/31057535
http://dx.doi.org/10.3389/fimmu.2019.00770

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