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Computational modeling of the olfactory receptor Olfr73 suggests a molecular basis for low potency of olfactory receptor-activating compounds

The mammalian olfactory system uses hundreds of specialized G-protein-coupled olfactory receptors (ORs) to discriminate a nearly unlimited number of odorants. Cognate agonists of most ORs have not yet been identified and potential non-olfactory processes mediated by ORs are unknown. Here, we used mo...

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Detalles Bibliográficos
Autores principales: Yuan, Shuguang, Dahoun, Thamani, Brugarolas, Marc, Pick, Horst, Filipek, Slawomir, Vogel, Horst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478719/
https://www.ncbi.nlm.nih.gov/pubmed/31044166
http://dx.doi.org/10.1038/s42003-019-0384-8