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A novel retroviral vector system to analyze expression from mRNA with retained introns using fluorescent proteins and flow cytometry

The ability to overcome cellular restrictions that exist for the export and translation of mRNAs with retained introns is a requirement for the replication of retroviruses and also for the expression of many mRNA isoforms transcribed from cellular genes. In some cases, RNA structures have been ident...

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Detalles Bibliográficos
Autores principales: Jackson, Patrick E. H., Huang, Jing, Sharma, Monika, Rasmussen, Sara K., Hammarskjold, Marie-Louise, Rekosh, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478720/
https://www.ncbi.nlm.nih.gov/pubmed/31015546
http://dx.doi.org/10.1038/s41598-019-42914-3