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A novel retroviral vector system to analyze expression from mRNA with retained introns using fluorescent proteins and flow cytometry
The ability to overcome cellular restrictions that exist for the export and translation of mRNAs with retained introns is a requirement for the replication of retroviruses and also for the expression of many mRNA isoforms transcribed from cellular genes. In some cases, RNA structures have been ident...
Autores principales: | Jackson, Patrick E. H., Huang, Jing, Sharma, Monika, Rasmussen, Sara K., Hammarskjold, Marie-Louise, Rekosh, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478720/ https://www.ncbi.nlm.nih.gov/pubmed/31015546 http://dx.doi.org/10.1038/s41598-019-42914-3 |
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