Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive- and anxiety-like behaviour, and gut microbiome composition

Converging evidence supports the involvement of pro-inflammatory pathways and the gut microbiome in major depressive disorder (MDD). Pre-clinical and clinical studies suggest that decreasing pro-inflammatory signaling may provide clinical benefit in MDD. In this study, we used the chronic unpredicta...

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Detalles Bibliográficos
Autores principales: Inserra, Antonio, Choo, Jocelyn M., Lewis, Martin D., Rogers, Geraint B., Wong, Ma-Li, Licinio, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478737/
https://www.ncbi.nlm.nih.gov/pubmed/31015500
http://dx.doi.org/10.1038/s41598-018-38055-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478737/
https://www.ncbi.nlm.nih.gov/pubmed/31015500
http://dx.doi.org/10.1038/s41598-018-38055-8

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