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Chicken DDX3X Activates IFN-β via the chSTING-chIRF7-IFN-β Signaling Axis

Asp-Glu-Ala-Asp (DEAD)-box polypeptide 3 X-linked (DDX3X) is an ATP-dependent RNA helicase, In addition to involvement of eukaryotic gene expression regulation, mammalian DDX3X has recently been found to regulate IFN-β production via the adaptor MAVS mediated cascade signaling. In our studies, we de...

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Detalles Bibliográficos
Autores principales: Niu, Qiaona, Cheng, Yuqiang, Wang, Hengan, Yan, Yaxian, Sun, Jianhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478769/
https://www.ncbi.nlm.nih.gov/pubmed/31057547
http://dx.doi.org/10.3389/fimmu.2019.00822