Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling

Sanguinarine (SNG), a benzophenanthridine alkaloid, has displayed various anticancer abilities in several vivo and in vitro studies. However, the anticancer potential of SNG is yet to be established in multiple myeloma (MM), a mostly incurable malignancy of plasma cells. In this study, we aimed to i...

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Detalles Bibliográficos
Autores principales: Akhtar, Sabah, Achkar, Iman W., Siveen, Kodappully S., Kuttikrishnan, Shilpa, Prabhu, Kirti S., Khan, Abdul Q., Ahmed, Eiman I., Sahir, Fairooz, Jerobin, Jayakumar, Raza, Afsheen, Merhi, Maysaloun, Elsabah, Hesham M., Taha, Ruba, Omri, Halima El, Zayed, Hatem, Dermime, Said, Steinhoff, Martin, Uddin, Shahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478801/
https://www.ncbi.nlm.nih.gov/pubmed/31058086
http://dx.doi.org/10.3389/fonc.2019.00285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478801/
https://www.ncbi.nlm.nih.gov/pubmed/31058086
http://dx.doi.org/10.3389/fonc.2019.00285

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