Aeration and Shear Stress Are Critical Process Parameters for the Production of Oncolytic Measles Virus

Oncolytic Measles virus is a promising candidate for cancer treatment, but clinical studies have shown that extremely high doses (up to 10(11) TCID(50) per dose) are required to effect a cure. Very high titers of the virus must therefore be achieved during production to ensure an adequate supply. We...

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Detalles Bibliográficos
Autores principales: Grein, Tanja A., Loewe, Daniel, Dieken, Hauke, Weidner, Tobias, Salzig, Denise, Czermak, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478815/
https://www.ncbi.nlm.nih.gov/pubmed/31058145
http://dx.doi.org/10.3389/fbioe.2019.00078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478815/
https://www.ncbi.nlm.nih.gov/pubmed/31058145
http://dx.doi.org/10.3389/fbioe.2019.00078

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