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Aeration and Shear Stress Are Critical Process Parameters for the Production of Oncolytic Measles Virus
Oncolytic Measles virus is a promising candidate for cancer treatment, but clinical studies have shown that extremely high doses (up to 10(11) TCID(50) per dose) are required to effect a cure. Very high titers of the virus must therefore be achieved during production to ensure an adequate supply. We...
Autores principales: | Grein, Tanja A., Loewe, Daniel, Dieken, Hauke, Weidner, Tobias, Salzig, Denise, Czermak, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478815/ https://www.ncbi.nlm.nih.gov/pubmed/31058145 http://dx.doi.org/10.3389/fbioe.2019.00078 |
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