A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors

Cryptosporidiosis is a leading cause of life-threatening diarrhea in children, and the only currently approved drug is ineffective in malnourished children and immunocompromised people. Large-scale phenotypic screens are ongoing to identify anticryptosporidial compounds, but optimal approaches to pr...

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Detalles Bibliográficos
Autores principales: Jumani, Rajiv S., Hasan, Muhammad M., Stebbins, Erin E., Donnelly, Liam, Miller, Peter, Klopfer, Connor, Bessoff, Kovi, Teixeira, Jose E., Love, Melissa S., McNamara, Case W., Huston, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478823/
https://www.ncbi.nlm.nih.gov/pubmed/31015448
http://dx.doi.org/10.1038/s41467-019-09880-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478823/
https://www.ncbi.nlm.nih.gov/pubmed/31015448
http://dx.doi.org/10.1038/s41467-019-09880-w

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