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SMAD3 directly regulates cell cycle genes to maintain arrest in granulosa cells of mouse primordial follicles

Primordial follicles, consisting of granulosa cell (GC)-enveloped oocytes are maintained in a state of developmental arrest until activated to grow. The mechanism that operates to maintain this arrested state in GCs is currently unknown. Here, we show the TGFβ-activated transcription factor SMAD3 is...

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Detalles Bibliográficos
Autores principales:	Granados-Aparici, Sofia, Hardy, Kate, Franks, Stephen, Sharum, Isam B., Waite, Sarah L., Fenwick, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478827/ https://www.ncbi.nlm.nih.gov/pubmed/31015579 http://dx.doi.org/10.1038/s41598-019-42878-4

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