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Identification of Prolyl isomerase Pin1 as a novel positive regulator of YAP/TAZ in breast cancer cells

The Hippo signalling pathway plays very important roles in tumorigenesis, metastasis, organ size control, and drug resistance. Although, it has been shown that the two major components of Hippo pathway, YAP and TAZ, play very crucial role in tumorigenesis and drug resistance, the exact molecular mec...

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Detalles Bibliográficos
Autores principales: Khanal, Prem, Yeung, Benjamin, Zhao, Yulei, Yang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478839/
https://www.ncbi.nlm.nih.gov/pubmed/31015482
http://dx.doi.org/10.1038/s41598-019-42767-w