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A 3.8 Å resolution cryo-EM structure of a small protein bound to an imaging scaffold
Proteins smaller than about 50 kDa are currently too small to be imaged at high resolution by cryo-electron microscopy (cryo-EM), leaving most protein molecules in the cell beyond the reach of this powerful structural technique. Here we use a designed protein scaffold to bind and symmetrically displ...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478846/ https://www.ncbi.nlm.nih.gov/pubmed/31015551 http://dx.doi.org/10.1038/s41467-019-09836-0 |