2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice

Aryl hydrocarbon receptor (AhR) activation is reported to alter the hepatic expression of circadian clock regulators, however the impact on clock-controlled metabolism has not been thoroughly investigated. This study examines the effects of AhR activation on hepatic transcriptome and metabolome rhyt...

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Detalles Bibliográficos
Autores principales: Fader, Kelly A., Nault, Rance, Doskey, Claire M., Fling, Russell R., Zacharewski, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478849/
https://www.ncbi.nlm.nih.gov/pubmed/31015483
http://dx.doi.org/10.1038/s41598-019-42760-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478849/
https://www.ncbi.nlm.nih.gov/pubmed/31015483
http://dx.doi.org/10.1038/s41598-019-42760-3

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