Characterization of Three Novel H3F3A-mutated Giant Cell Tumor Cell Lines and Targeting of Their Wee1 Pathway

The giant cell tumor of bone (GCTB) is a locally aggressive primary bone tumor that is composed of mononuclear stroma cells, scattered macrophages, and multinucleated osteoclast-like giant cells which cause pathologic osteolysis. The stroma cells represent the neoplastic population of the tumor and...

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Detalles Bibliográficos
Autores principales: Lübbehüsen, Christoph, Lüke, Julian, Seeling, Carolin, Mellert, Kevin, Marienfeld, Ralf, von Baer, Alexandra, Schultheiss, Markus, Möller, Peter, Barth, Thomas F. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478864/
https://www.ncbi.nlm.nih.gov/pubmed/31015476
http://dx.doi.org/10.1038/s41598-019-42611-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478864/
https://www.ncbi.nlm.nih.gov/pubmed/31015476
http://dx.doi.org/10.1038/s41598-019-42611-1

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