Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism

Transcriptional reprogramming of cellular metabolism is a hallmark of cancer. However, systematic approaches to study the role of transcriptional regulators (TRs) in mediating cancer metabolic rewiring are missing. Here, we chart a genome-scale map of TR-metabolite associations in human cells using...

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Detalles Bibliográficos
Autores principales: Ortmayr, Karin, Dubuis, Sébastien, Zampieri, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478870/
https://www.ncbi.nlm.nih.gov/pubmed/31015463
http://dx.doi.org/10.1038/s41467-019-09695-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478870/
https://www.ncbi.nlm.nih.gov/pubmed/31015463
http://dx.doi.org/10.1038/s41467-019-09695-9

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