The cyclooxygenase-1/mPGES-1/endothelial prostaglandin EP4 receptor pathway constrains myocardial ischemia-reperfusion injury

The use of nonsteroidal anti-inflammatory drugs that inhibit cyclooxygenase (COX)-1 and COX-2, increases heart failure risk. It is unknown whether microsomal (m) prostaglandin (PG) E synthase (S)-1, a target downstream of COX, regulates myocardial (M) ischemia/reperfusion (I/R) injury, a key determi...

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Detalles Bibliográficos
Autores principales: Zhu, Liyuan, Xu, Chuansheng, Huo, Xingyu, Hao, Huifeng, Wan, Qing, Chen, Hong, Zhang, Xu, Breyer, Richard M., Huang, Yu, Cao, Xuetao, Liu, De-Pei, FitzGerald, Garret A., Wang, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478873/
https://www.ncbi.nlm.nih.gov/pubmed/31015404
http://dx.doi.org/10.1038/s41467-019-09492-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478873/
https://www.ncbi.nlm.nih.gov/pubmed/31015404
http://dx.doi.org/10.1038/s41467-019-09492-4

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