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Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors

Nanoparticles can potentially stimulate tumour microenvironments to elicit antitumour immunity. Herein, we demonstrate effective immunotherapy of colorectal cancer via systemic delivery of an immunostimulatory chemotherapeutic combination in nanoscale coordination polymer (NCP) core-shell particles....

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Detalles Bibliográficos
Autores principales: Duan, Xiaopin, Chan, Christina, Han, Wenbo, Guo, Nining, Weichselbaum, Ralph R., Lin, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478897/
https://www.ncbi.nlm.nih.gov/pubmed/31015397
http://dx.doi.org/10.1038/s41467-019-09221-x